language.” Some topics the Council
initially focused on included:
• Establishment of Global IACUC
Guidelines such as acclimation peri-
ods, restraint, blood collection, etc.
• Evaluation of concerns on the radar
of regulatory agencies and AAALAC,
such as animal enrichment, pain/
distress categories, and post approval
• Inspections and review of facilities
• Handling of IACUC investigations
Over the years, Pfizer has had acqui-
sitions, mergers, and other logistical
changes that have weighed heavily in
determining the focus of the Coun-
cil. Differences between European,
Canadian and American regulations
introduce another level of complexity.
Today, Pfizer has animal care and use
programs at ten worksites spanning
across the United States, Canada, and
the United Kingdom.
Council was formed.
Today, the Council examines animal welfare and ethical issues and
helps to encourage efficiency through
harmonization, standardization, and
implementation of best practices
within local IACUCs and AWBs. The
Council provides a forum for discussion of impactful issues or concerns,
sharing of best practices for remediation of incidents or investigations, and
dissemination of relevant information
gathered through Council members’
attendance at workshops, conferences,
symposiums, and training sessions. The
Council also promotes development of
Global IACUC guidelines and policies to
help standardize or harmonize animal
care and use.
The first meeting in 2006 established a
charter for expectations of the Council
including the vision, a value state-
ment, team scope, identification of key
stakeholders, membership requirements,
expectations, and additional resources.
Short-term and long-term deliverables
were prioritized and milestone time-
lines were established. Subcommittees
were also identified to assist in specific
Colleagues either expressed interest
in joining the Council or were nominated by site or global leadership and
then appointed by the ACWB. Animal
users, research scientists, regulatory,
compliance, veterinary, quality assurance, and other key colleagues who
sit on site IACUCs/AWBs comprise the
current membership on the Council.
This well-rounded membership helps
to provide a multi-faceted perspective
on a variety of issues that may arise in
each Pfizer site.
Alignment was accomplished by
harmonization of IACUC work processes and operations to improve
compliance and consistency. This also
enabled members to “speak the same
IACUCs/AWBs must align with governmental regulations in the US, Canada, the UK, European Union, state agencies, city/local ordinances
and AAALACi guidelines.